Reserve concomitant prescribing of those medicines in individuals for whom other treatment method possibilities are inadequate. Restrict dosages and durations to the minimum demanded. Monitor carefully for signs of respiratory depression and sedation.
I had a Seizure Motion Prepare which i properly trained All those close to me to employ After i had a seizure, but I still didn’t feel confident in my ability to Handle my seizures.” Newfound self esteem with VALTOCO
Connect with a Health care service provider right away Should you have any new or worsening suicidal thoughts or associated indicators, In particular strange variations in mood, behaviors, views or thoughts.
Muscle mass spasms; convulsions caused by epilepsy or fever; stress; agitation or sleeplessness connected with anxiety; stress attacks; being a pre-med just before surgical treatment or professional medical processes; together with other treatment options in alcohol withdrawal
Present extra seizure Handle: while not having to give up the advantages of your existing antiepileptic medicine(s)
Suicidal ideas or steps is usually caused by factors besides medicines. When you have suicidal ideas or steps, your Health care company might look for other brings about. Don't use VALTOCO when you:
cannabidiol will enhance the amount or influence of diazepam by influencing hepatic enzyme CYP2C19 metabolism. Modify Therapy/Keep an eye on Closely. Think about lessening website the dose of delicate CYP2C19 substrates, as clinically proper, when coadministered with cannabidiol.
“We discussed VALTOCO. We decided it absolutely was really worth a shot, and we labored together to make it a A part of my Seizure Action System. In my desk, I've a neon box I keep as an crisis kit for Once i Use a seizure.
Keep track of Intently (1)lenacapavir will boost the stage or result of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
Concomitant utilization of benzodiazepines and opioids might end in profound sedation, respiratory depression, coma, and death
Keep away from concomitant use of tucatinib with CYP3A substrates, the place nominal focus changes may well bring about severe or lifestyle-threatening toxicities. If unavoidable, minimize CYP3A substrate dose In line with product labeling.
istradefylline will improve the level or impact of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
artemether/lumefantrine will decrease the extent or effect of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
If not able to prevent coadministration of belzutifan with delicate CYP3A4 substrates, take into consideration rising the sensitive CYP3A4 substrate dose in accordance with its prescribing data.